Draw Me a Reason Asystole I drew an arrow. Therefore I proved the cause. Your pencil's asking for a lawyer. Start with the question: whose outcome, which choice? Compared with what, by when? Give the target a voice. Potential outcomes: what would happen under each plan; For the same decision, one observed path is all we can See for each person. The other stays unknown; Causal inference compares more than what's simply shown. Directed acyclic graph: a D-A-G; Arrows state causal assumptions for the world we think we see. Directed means the arrows have a way to go; Acyclic: no directed loop around the show. Time-indexed nodes let later feedback take its place; Keep earlier and later measurements in their proper space. Draw relevant shared causes and the routes they can create; An absent arrow also makes a claim to contemplate. You made a graph so pretty that the crowd began to clap; It still needs defensible assumptions underneath the map. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. A backdoor path starts with an arrow into treatment; Shared causes can make comparisons need refinement. Block the noncausal routes with a suitable measured set; Keep the causal question in the method that you vet. For a total effect, don't casually block the chain Through a mediator carrying the change you want to explain. Conditioning on a collider can open up a route; Your adjustment list needs reasons for who stays in or out. Observational data can support a causal aim; The assumptions and the design must carry that claim. Matching, weighting, regression: useful tools if they fit; Hidden common causes won't just vanish when you hit submit. Define eligibility and time zero with care; Align assignment and follow-up for a comparison that's fair. Immortal time can creep in if future survival picks a side; Emulate the target trial. Keep your starting clocks aligned. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. Consistency: observed outcomes match the treatment received, With well-defined interventions in the claim you've conceived. Exchangeability, conditional on the set: Potential outcomes independent of the treatment people get. Positivity: each option must be possible within The covariate groups your comparison is in. Measurement, missing causes, sensitivity checks: Tell me where the claim could bend before you flex. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. Draw me a reason, state what you assume. What would happen if we changed the choice in this room? A diagram makes the causal story clear; It doesn't make the hidden problems disappear. My graph has no unmeasured causes. Because you measured them? Because I didn't draw them. ...Pass the pencil.